INFINITE offers a unique research environment around inflammation. INFINITE welcomes scientists, clinicians doctors, pharmacists, students, manufacturers and innovators in a very open structure, which fosters creativity, promotes innovation and includes all types of skills.
You will find below our PhD program, internship and job offers.
Mobility offer - Assistant Engineer
INFINITE is looking for an Inserm Assistant Engineer in mobility
Post-doc position in medicinal chemistry
The candidate will join WP4 "Therapeutic innovation targeting inflammation" of the INFINITE research unit. The scientific objective of this team is the design, synthesis, biological evaluation and vectorization of new chemical entities for therapeutic purposes in the field of inflammatory diseases. The candidate will work more specifically with Doctor Natascha LELEU-CHAVAIN at ICPAL - Faculty of Pharmacy of Lille.
Key word: chemistry, medicinal
Profile and skills: Holder of a doctorate in organic chemistry or medicinal chemistry with ideally experience abroad, the candidate should have a marked attraction for research projects at the interface between chemistry and biology. Skills and knowledge in organic synthesis as well as in drug sciences are essential in order to allow work in collaboration with physical chemists and biologists. Knowledge of molecular modeling would be a plus.
Dynamic and rigorous, the candidate will have to show organization, creativity and initiative. He (She) must have good interpersonal skills, and like teamwork. Concerned about the achievement of his (her) objectives, he (she) will have a marked interest in the management of scientific projects.
Missions: The candidate will be integrated into the INODHEP project funded by the I-SITE ULNE Foundation. The objective of this multidisciplinary project is to develop inhibitors of the NOD1 pathway in order to limit hepatic damage from ischemia-reperfusion and thus improve the survival of transplant patients, but also to increase the number of available grafts. The preliminary results are very promising and allowed the identification of the first selective inhibitors of NOD1-RIPK2. The candidate will help strengthen the team by getting involved in this research project. He (She) will be in charge of the synthesis of innovative chemical series and the interpretation of the structure-activity relationships necessary for filing a patent.
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