Description and role of humoral immunity in systemic fibrosis diseases

Leader: David Launay

Workpackage: WP3

A. Role of B Lymphocytes

 

B. Evaluation of characteristics of autoantibodies functions in SSc and cGvHD

 

C. Evaluation of the impact of immunomodulation treatments in animal models

 Main Publications

Scientific articles

2018

  1. 1. Forestier A, Guerrier T, Jouvray M, Giovannelli J, Lefèvre G, Sobanski V, Hauspie C, Hachulla E, Hatron PY, Zephir H, Vermersch P, Labalette M, Launay D, Dubucquoi S*. Altered B lymphocyte homeostasis and functions in systemic sclerosis. Autoimmun Rev 2018 Mar;17(3):244-255. (IF : 8.961)
  2. 2. Guerrier T, Labalette M, Launay D, Lee-Chang C, Outteryck O, Lefèvre G, Vermersch P, Dubucquoi S, Zéphir H. Proinflammatory B-cell profile in the early phases of MS predicts an active disease. Neurol Neuroimmunol Neuroinflamm 2018;5:e431. (IF Neurology 8.320)
  3. 3. Jouvray M, Launay D, Dubucquoi S, Sobanski V, Podevin C, Lambert M, Morell-Dubois S, Maillard H, Hatron PY, Hachulla E, Giovannelli J*. Whole-Body Distribution and Clinical Association of Telangiectases in Systemic Sclerosis. JAMA Dermatol 2018 (in press). (IF : 5.82)
  4. 4. Grunewald O, Lopez B, Brabant S, Rogeau S, Deschildre A, Phrommavanh V, Lefort M, Moitrot E, Gyselinckx D, Deleplancque AS, Lefèvre G, Labalette M, Dubucquoi S.* Immunoglobulin G (IgG) and IgG subclass reference intervals in children, using Optilite® reagents. Clin Chem Lab Med.2018 (IF : 3,432)

2017

  1. 5. Sanges S, Jendoubi M, Kavian N, Hauspie C, Speca S, Crave JC, Guerrier T, Lefèvre G, Sobanski V, Savina A, Hachulla E, Hatron PY, Labalette M, Batteux F, Dubucquoi S, Launay D*. B Cell Homeostasis and Functional Properties Are Altered in an Hypochlorous Acid-Induced Murine Model of Systemic Sclerosis. Front Immunol 2017;8. (IF : 6.429)

2016

  1. 6. Sobanski V, Giovannelli J, Lynch BM, Schreiber BE, Nihtyanova SI, Harvey J, Handler CE, Denton CP, Coghlan JG. Characteristics and Survival of Anti-U1 RNP Antibody-Positive Patients With Connective Tissue Disease-Associated Pulmonary Arterial Hypertension.. Arthritis Rheumatol. 2016; 68:484-93. (IF : 6,918)
  2. 7. Bertin D, Dubucquoi S, Lakomy D, Deleplancque AS, Desplat-Jégo S. Diagnostic performance of a new vimentin-derived ACPA (CCP high sensitive) in patients with rheumatoid arthritis. Immunol. Res. 2016. 64, 455–460 (IF : 2.905)

2015

  1. 8. Dutoit-Lefevre V, Dubucquoi S, Launay D, Sobanski V, Dussart P, Chafey P, Broussard C, Duban-Deweer S, Vermersch P, Prin L, Lefranc D*. An Optimized Fluorescence-Based Bidimensional Immunoproteomic Approach for Accurate Screening of Autoantibodies. PLoS One 2015;10. (IF : 2.806)
  2. 9. Pascal L, Hivert B, Trauet J, Deberranger E, Dessaint JP, Yakoub-Agha I, Labalette M*. A low effective dose of interleukin-7 is sufficient to maintain cord blood T cells alive without potentiating allo-immune responses. Biol Blood Marrow Transplant. 2015 Apr;21(4):625-31. (IF : 4,704)
  3. 10. Gatault S, Delbeke M, Driss V, Sarazin A, Dendooven A, Kahn JE, Lefèvre G, Capron M*. IL-18 Is Involved in Eosinophil-Mediated Tumoricidal Activity against a Colon Carcinoma Cell Line by Upregulating LFA-1 and ICAM-1. J Immunol. 2015;195:2483-92. (IF : 4.856)
  4. 11. Mortuaire G, Gengler I, Vandenhende-Szymanski C, Delbeke M, Gatault S, Chevalier D, Prin L, Capron M. Immune profile modulation of blood and mucosal eosinophils in nasal polyposis with concomitant asthma. Ann Allergy Asthma Immunol. 2015; 15: S1081-1206. (IF : 3.728)
  5. 12. Dubucquoi S, Proust-Lemoine E, Kemp EH, Ryndak A, Lefevre-Dutoit V, Bellart M, Saugier-Veber P, Duban-Deweer S, Wemeau JL, Prin L, Lefranc D*. Serological proteome analysis reveals new specific biases in the IgM and IgG autoantibody repertoires in autoimmune polyendocrine syndrome type 1. Autoimmunity 2015. 48, 532–541(IF : 2,629)

2014

  1. 13. Sobanski V, Dauchet L, Lefevre G, Lambert M, Morell-Dubois S, Sy T, Hachulla E, Hatron PY, Launay D, Dubucquoi S*. Prevalence of Anti-RNA Polymerase III Antibodies in Systemic Sclerosis New Data From a French Cohort and a Systematic Review and Meta-Analysis. Arthritis Rheumatol 2014;66:407-17. (IF : 6,918)
  2. 14. Lanteri A, Sobanski V, Langlois C, Lefevre G, Hauspie C, Sanges S, Lambert M, Morell-Dubois S, Hatron PY, Hachulla E, Launay D, Dubucquoi S*. Serum free light chains of immunoglobulins as biomarkers for systemic sclerosis characteristics, activity and severity. Autoimmun Rev 2014;13:974-80. (IF : 8.961)
  3. 15. Choufi B, Trauet J, Thiant S, Labalette M, Yakoub-Agha I*. Donor-derived CD4+/CCR7+ T-cell partiel selective depletion does not alter acquired anti-infective immunity. Bone Marrow Transplant, 2014, 49 (5):611-615. (IF : 3.874)
  4. 16. Chérel M, Choufi B, Trauet J, Cracco P, Dessaint JP, Yakoub-Agha I, Labalette M*. Naïve subset develops the most important alloreactive response among human CD4+ T lymphocytes in human leukocyte antigen-identical related setting. Eur J Haematol. 2014;92(6):491-6. (IF : :2.653)
  5. 17. Lorenzi R, Pattou F, Beuscart JB, Grossin N, Lambert M, Fontaine P, Caiazzo R, Pigeyre M, Patrice A, Daroux M, Boulanger E, Dubucquoi S*. Anti-sRAGE autoimmunity in obesity: Downturn after bariatric surgery is independent of previous diabetic status. Diabetes Metab. 2014. 40, 356–362 (IF : 4,101)
  6. 18. Duchamp M, Sterlin D, Diabate A, Uring-Lambert B, Guérin-El Khourouj V, Le Mauff B, Monnier D, Malcus C, Labalette M, Picard C. B-cell subpopulations in children: National reference values. Immun Inflamm Dis. 2014 ;2(3):131-40.

2013

  1. 19. Lauwerys BR, Hachulla E, Spertini F, Lazaro E, Jorgensen C, Mariette X, Haelterman E, Grouard-Vogel G, Fanget B, Dhellin O, Vandepapelière P, Houssiau FA. Down-regulation of interferon signature in systemic lupus erythematosus patients by active immunization with interferon α-kinoid. Arthritis Rheum. 2013;65:447-56. (IF : 6,918)
  2. 20. Scherpereel A, Grigoriu BD, Noppen M, Gey T, Chahine B, Baldacci S, Trauet J, Copin MC, Dessaint JP, Porte H, Labalette M*. Defect in recruiting effector memory CD8+ T-cells in malignant pleural effusions compared to normal pleural fluid. BMC Cancer. 2013;13:324. (IF : 3,288)
  3. 21. Launay D, Dutoit-Lefevre V, Faure E, Robineau O, Hauspie C, Sobanski V, Hachulla E, Labalette M, Hatron PY, Dubucquoi S*. Effect of In Vitro and In Vivo Anakinra on Cytokines Production in Schnitzler Syndrome. PLoS One 2013;8. (IF : 2.806)
  4. 22. Maire C, Vercambre-Darras S, Devos P, D’Herbomez M, Dubucquoi S, Mortier L. Metastatic melanoma: spontaneous occurrence of auto antibodies is a good prognosis factor in a prospective cohort. J. Eur. Acad. Dermatol. Venereol. 2013. 27, 92–96 (IF : 3,528)

Clinical articles

2018

  1. 1. Launay D, Montani D, HAssoun PM, Cottin V, Le Pavec J, Clerson P, Sitbon O, Jaïs X, Savale L, Weatherald J, Sobanski V, Mathai SC, Shafiq M, Cordier JF, Hachulla E, Simonneau G, Humbert M. Clinical phenotypes and survival of pre-capillary pulmonary hypertension in systemic sclerosis. PLOS One 2018 (in press) (IF : 2.806)
  2. 2. Thiebaut M, Launay D, Rivière S, Mahévas T, Bellakhal S, Hachulla E, Fain O, Mekinian A. Efficacy and safety of rituximab in systemic sclerosis: French retrospective study and literature review. Autoimmun Rev 2018. (IF : 8.961)
  3. 3. Jaeger VK, Valentini G, Hachulla E, Cozzi F, Distler O, Airó P, Czirják L, Allanore Y, Siegert E, Rosato E, Matucci-Cerinic M, Caimmi C, Henes J, Carreira PE, Smith V, Del Galdo F, Denton CP, Ullman S, Langhe E, Riccieri V, Alegre-Sancho JJ, Rednic S, Müller-Ladner U, Walker UA; EUSTAR co-authors. Smoking in Systemic Sclerosis: a Longitudinal European Scleroderma Trials and Research Group Study. Arthritis Rheumatol. 2018 (IF : 6.918)
  4. 4. Martis N, Queyrel-Moranne V, Launay D, Neviere R, Fuzibet JG, Marquette CH, Leroy S. Limited Exercise Capacity in Patients with Systemic Sclerosis: Identifying Contributing Factors with Cardiopulmonary Exercise Testing. J Rheumatol 2018;45:95-102. (IF : 3.15)
  5. 5. Hachulla E, Jais X, Cinquetti G, Clerson P, Rottat L, Launay D, Cottin V, Habib G, Prevot G, Chabanne C, Fois E, Amoura Z, Mouthon L, Le Guern V, Montani D, Simonneau G, Humbert M, Sobanski V, Sitbon O. Pulmonary Arterial Hypertension Associated With Systemic Lupus Erythematosus Results From the French Pulmonary Hypertension Registry. Chest 2018;153:143-51. (IF : 6.147)
  6. 6. Giovannelli, J., Trouiller, P., Hulo, S., Chérot-Kornobis, N., Ciuchete, A., Edmé, J.-L., Matran, R., Amouyel, P., Meirhaeghe, A., and Dauchet, L. Low-grade systemic inflammation: a partial mediator of the relationship between diabetes and lung function. Ann. Epidemiol. 2018 Jan; 28, 26–32. (IF : 2.582)
  7. 7. Forestier A, Buob D, Mirault T, Puech P, Gnemmi V, Launay D, Hachulla E, Hatron PY, Lambert M. No specific imaging pattern can help differentiate IgG4-related disease from idiopathic retroperitoneal fibrosis: 18 histologically proven cases. Clin Exp Rheumatol 2018. (IF : 2.634)
  8. 8. Lopez B, Boucher A, Bahuaud M, Mortuaire G, Melliez H, Launay D, Terriou L, Wemeau-Stervinou L, Wallaert B, Faure K, Wallet F, Hachulla E, Hatron PY, Dubucquoi S, Batteux F, Labalette M, Lefevre G*. Polysaccharide Antibody Deficiency: Specific or General? Reply. Clin Infect Dis 2018;66:637-8. (IF : 8.216)

2017

  1. 9. Sanges S, Rivière S, Mekinian A, Martin T, Le Quellec A, Chatelus E, Lescoat A, Jego P, Cazalets C, Quéméneur T, Le Gouellec N, Senet P, Francès C, Deroux A, Imbert B, Fain O, Boukari L, Sené T, Deligny C, Mathian A, Agard C, Pugnet G, Speca S, Dubucquoi S, Hatron PY, Hachulla É, Launay D*. Intravenous immunoglobulins in systemic sclerosis: Data from a French nationwide cohort of 46 patients and review of the literature. Autoimmun Rev 2017;16:377-84 (IF : 8.961)
  2. 10. Denton CP, Hachulla É, Riemekasten G, Schwarting A, Frenoux JM, Frey A, Le Brun FO, Herrick AL; Raynaud Study Investigators. Efficacy and Safety of Selexipag in Adults With Raynaud's Phenomenon Secondary to Systemic Sclerosis: A Randomized, Placebo-Controlled, Phase II Study. Arthritis Rheumatol. 2017 Dec;69(12):2370-2379. (IF : 6.918)
  3. 11. Sanges S, Giovannelli J, Sobanski V, Morell-Dubois S, Maillard H, Lambert M, Podevin C, Lamblin N, De Groote P, Bervar JF, Perez T, Matran R, Remy-Jardin M, Hatron PY, Hachulla E, Launay D*. Factors associated with the 6-minute walk distance in patients with systemic sclerosis. Arthritis Res Ther 2017;19. (IF : 4.121)
  4. 12. Le Gouellec N, Duhamel A, Perez T, Hachulla AL, Sobanski V, Faivre JB, Morell-Dubois S, Lambert M, Hatron PY, Hachulla E, Béhal H, Matran R, Launay D*, Remy-Jardin M. Predictors of lung function test severity and outcome in systemic sclerosis-associated interstitial lung disease. PLoS One 2017;12. (IF : 2.806)
  5. 13. Sanges S, Wallet F, Blondiaux N, Theis D, Verin I, Vachee A, Dessein R, Faure K, Viget N, Senneville E, Leroy O, Maury F, Just N, Poissy J, Mathieu D, Prevotat A, Chenivesse C, Scherpereel A, Smith G, Lopez B, Rosain J, Fremeaux-Bacchi V, Hachulla E, Hatron PY, Bahuaud M, Batteux F, Launay D, Labalette M, Lefevre G*. Diagnosis of primary antibody and complement deficiencies in young adults after a first invasive bacterial infection. Clin Microbiol Infect 2017;23. (IF : 5.292)
  6. 14. Lopez B, Boucher A, Bahuaud M, Mortuaire G, Melliez H, Launay D, Terriou L, Wemeau-Stervinou L, Wallaert B, Faure K, Wallet F, Hachulla E, Hatron PY, Dubucquoi S, Batteux F, Labalette M, Lefevre G*. Specific Polysaccharide Antibody Deficiency Revealed by Severe Bacterial Infections in Adulthood: A Report on 11 Cases. Clin Infect Dis 2017;65:328-31 (IF : 8.216)
  7. 15. Lopez B, Bahuaud M, Fieschi C, Mehlal S, Jeljeli M, Rogeau S, Brabant S, Deleplancque AS, Dubucquoi S, Poizot S, Terriou L, Launay D, Batteux F, Labalette M, Lefevre G*. Value of the Overall Pneumococcal Polysaccharide Response in the Diagnosis of Primary Humoral Immunodeficiencies. Front Immunol 2017;8. (IF : 6.429)
  8. 16. Revuz S, Decullier E, Ginon I, Lamblin N, Hatron PY, Kaminsky P, Carette MF, Lacombe P, Simon AC, Rivière S, Harlé JR, Fraisse A, Lavigne C, Leguy-Seguin V, Chaouat A, Khouatra C, Dupuis-Girod S, Hachulla E*. Pulmonary hypertension subtypes associated with hereditary haemorrhagic telangiectasia: Haemodynamic profiles and survival probability. PLoS One. 2017 Oct 5;12(10):e0184227. (IF : 2.806)
  9. 17. Durtette C, Hachulla E, Resche-Rigon M, Papo T, Zénone T, Lioger B, Deligny C, Lambert M, Landron C, Pouchot J, Kahn JE, Lavigne C, De Wazieres B, Dhote R, Gondran G, Pertuiset E, Quemeneur T, Hamidou M, Sève P, Le Gallou T, Grasland A, Hatron PY, Fain O, Mekinian A; SNFMI and CRI. Cogan syndrome: Characteristics, outcome and treatment in a French nationwide retrospective study and literature review. Autoimmun Rev. 2017 Dec;16(12):1219-1223. doi: 10.1016/j.autrev.2017.10.005. Epub 2017 Oct 14. Review. (IF : 8.961)

2016

  1. 21. Sanges S, Launay D, Rhee RL, Sitbon O, Hachulla É, Mouthon L, Guillevin L, Rottat L, Montani D, De Groote P, Cottin V, Magro P, Prévot G, Bauer F, Bergot E, Chabanne C, Reynaud-Gaubert M, Leroy S, Canuet M, Sanchez O, Gut-Gobert C, Dauphin C, Pison C, Boissin C, Habib G, Clerson P, Conesa F, Cordier JF, Kawut SM, Simonneau G, Humbert M. A prospective study of the 6 min walk test as a surrogate marker for haemodynamics in two independent cohorts of treatment-naive systemic sclerosis-associated pulmonary arterial hypertension. Ann Rheum Dis 2016;75:1457-65. (IF : 12.811)
  2. 22. Hachulla E, Hatron PY, Carpentier P, Agard C, Chatelus E, Jego P, Mouthon L, Queyrel V, Fauchais AL, Michon-Pasturel U, Jaussaud R, Mathian A, Granel B, Diot E, Farge-Bancel D, Mekinian A, Avouac J, Desmurs-Clavel H, Clerson P. Efficacy of sildenafil on ischaemic digital ulcer healing in systemic sclerosis: the placebo-controlled SEDUCE study. Ann Rheum Dis 2016;75:1009-15. (IF : 12.811)
  3. 23. Sanges S, Yelnik CM, Sitbon O, Benveniste O, Mariampillai K, Phillips-Houlbracq M, Pison C, Deligny C, Inamo J, Cottin V, Mouthon L, Launay D, Lambert M, Hatron PY, Rottat L, Humbert M, Hachulla E*. Pulmonary arterial hypertension in idiopathic inflammatory myopathies: Data from the French pulmonary hypertension registry and review of the literature. Medicine (Baltimore) 2016;95. (IF : 1.804)
  4. 24. Hachulla E, Benveniste O, Hamidou M, Mouthon L, Schleinitz N, Lozeron P, Léger JM, Vial C, Viala K. High dose subcutaneous immunoglobulin for idiopathic inflammatory myopathies and dysimmune peripheral chronic neuropathies treatment: observational study of quality of life and tolerance. Int J Neurosci. 2016 Jul 14:1-8. (IF : 1.75)
  5. 25. Avouac J, Walker UA, Hachulla E, Riemekasten G, Cuomo G, Carreira PE, Caramaschi P, Ananieva LP, Matucci-Cerinic M, Czirjak L, Denton C, Ladner UM, Allanore Y; EUSTAR collaborators*; EUSTAR collaborators. Joint and tendon involvement predict disease progression in systemic sclerosis: a EUSTAR prospective study. Ann Rheum Dis. 2016 Jan;75(1):103-9 (IF : 12.811)
  6. 26. Giovannelli, J., Chérot-Kornobis, N., Hulo, S., Ciuchete, A., Clément, G., Amouyel, P., Matran, R., and Dauchet, L. Both exhaled nitric oxide and blood eosinophil count were associated with mild allergic asthma only in non-smokers. Clin. Exp. Allergy J. Br. Soc. Allergy Clin. Immunol. 2016 Apr; 46, 543–554. (IF : 5.264)

2015

  1. 27. Hachulla E, Clerson P, Airò P, Cuomo G, Allanore Y, Caramaschi P, Rosato E, Carreira PE, Riccieri V, Sarraco M, Denton CP, Riemekasten G, Pozzi MR, Zeni S, Mihai CM, Ullman S, Distler O, Rednic S, Smith V, Walker UA, Matucci-Cerinic M, Müller-Ladner U, Launay D*. Value of systolic pulmonary arterial pressure as a prognostic factor of death in the systemic sclerosis EUSTAR population. Rheumatology 2015;54:1262-9. (IF : 4.818)
  2. 28. Lefevre G, Meyer A, Launay D, Machelart I, DeBandt M, Michaud J, Tournadre A, Godmer P, Kahn JE, Behra-Marsac A, Timsit MA, Schleinitz N, Wendling D, Melac-Ducamp S, Boyer P, Peretz A, Lequerre T, Richez C, Stervinou-Wemeau L, Morell-Dubois S, Lambert M, Dubucquoi S, Wallaert B, Benveniste O, Flipo RM, Hatron PY, Sibilia J, Hachulla E, Hervier B. Seronegative polyarthritis revealing antisynthetase syndrome: a multicentre study of 40 patients. Rheumatology 2015;54:927-32. (IF : 4.818)
  3. 29. Pascal L, Mohty M, Ruggeri A, Tucunduva L, Milpied N, Chevallier P, Tabrizi R, Labalette M, Gluckman E, Labopin M, *Yakoub-Agha I. Impact of rabbit ATG-containing myeloablative conditioning regimens on the outcome of patients undergoing unrelated single-unit cord blood transplantation for hematological malignancies. Bone Marrow Transplant. 2015;50(1):45-50. (IF : 3.874)
  4. 30. Lefevre G, Copin MC, Roumier C, Aubert H, Avenel-Audran M, Grarde N, Poulain S, Staumont-Salle D, Seneschal J, Salles G, Ghomari K, Terriou L, Leclech C, Morati-Hafsaoui C, Morschhauser F, Lambotte O, Ackerman F, Trauet J, Geffroy S, Dumezy F, Capron M, Roche-Lestienne C, Taieb A, Hatron PY, Dubucquoi S, Hachulla E, Prin L, Labalette M, Launay D, Preudhomme C, Kahn JE. CD3(-)CD4(+) lymphoid variant of hypereosinophilic syndrome: nodal and extranodal histopathological and immunophenotypic features of a peripheral indolent clonal T-cell lymophoproliferative disorder. Haematologica 2015;100:1086-95. (IF : 7.702)
  5. 31. Houx L, Hachulla E, Kone-Paut I, Quartier P, Touitou I, Guennoc X, Grateau G, Hamidou M, Neven B, Berthelot JM, Lequerré T, Pillet P, Lemelle I, Fischbach M, Duquesne A, Le Blay P, Le Jeunne C, Stirnemann J, Bonnet C, Gaillard D, Alix L, Touraine R, Garcier F, Bedane C, Jurquet AL, Duffau P, Smail A, Frances C, Grall-Lerosey M, Cathebras P, Tran TA, Morell-Dubois S, Pagnier A, Richez C, Cuisset L, Devauchelle-Pensec V. Musculoskeletal symptoms in patients with cryopyrin-associated periodic syndromes: a large database study. Arthritis Rheumatol. 2015 Nov;67(11):3027-36. (IF : 6.918)
  6. 32. van Laar JM, Farge D, Sont JK, Naraghi K, Marjanovic Z, Larghero J, Schuerwegh AJ, Marijt EWA, Vonk MC, Schattenberg AV, Matucci-Cerinic M, Voskuyl AE, van de Loosdrecht AA, Daikeler T, Kotter I, Schmalzing M, Martin T, Lioure B, Weiner SM, Kreuter A, Deligny C, Durand JM, Emery P, Machold KR, Sarrot-Reynauld F, Warnatz K, Adoue DFP, Constans J, Tony HP, Del Papa N, Fassas A, Himsel A, Launay D, Lo Monaco A, Philippe P, Quere I, Rich E, Westhovens R, Griffiths B, Saccardi R, van den Hoogen FH, Fibbe WE, Socie G, Gratwohl A, Tyndall A. Autologous Hematopoietic Stem Cell Transplantation vs Intravenous Pulse Cyclophosphamide in Diffuse Cutaneous Systemic Sclerosis A Randomized Clinical Trial. JAMA-J Am Med Assoc 2014;311:2490-8. (IF : 44.405)

2014

  1. 35. Launay D, Savale L, Berezne A, Le Pavec J, Hachulla E, Mouthon L, Sitbon O, Lambert B, Gaudric M, Jais X, Stephan F, Hatron PY, Lamblin N, Vignaux O, Cottin V, Farge D, Wallaert B, Guillevin L, Simonneau G, Mercier O, Fadel E, Dartevelle P, Humbert M, Mussot S. Lung and heart-lung transplantation for systemic sclerosis patients. A monocentric experience of 13 patients, review of the literature and position paper of a multidisciplinary Working Group. Presse Med 2014;43:E345-E63. (IF : 1.071)
  2. 36. Lefevre G, Copin MC, Staumont-Salle D, Avenel-Audran M, Aubert H, Taieb A, Salles G, Maisonneuve H, Ghomari K, Ackerman F, Legrand F, Baruchel A, Launay D, Terriou L, Leclech C, Khouatra C, Morati-Hafsaoui C, Labalette M, Borie R, Cotton F, Le Gouellec N, Morschhauser F, Trauet J, Roche-Lestienne C, Capron M, Hatron PY, Prin L, Kahn JE. The Lymphoid Variant of Hypereosinophilic Syndrome Study of 21 Patients With CD3-CD4+ Aberrant T-Cell Phenotype. Medicine (Baltimore) 2014;93:255-66. (IF : 1.804)
  3. 37. Heusele M, Clerson P, Guery B, Lambert M, Launay D, Lefevre G, Morell-Dubois S, Maillard H, Le Gouellec N, Hatron PY, Hachulla E*. Risk factors for severe bacterial infections in patients with systemic autoimmune diseases receiving rituximab. Clin Rheumatol 2014;33:799-805. (IF : 2.365)

2013

  1. 38. Lefevre G, Dauchet L, Hachulla E, Montani D, Sobanski V, Lambert M, Hatron PY, Humbert M, Launay D*. Survival and Prognostic Factors in Systemic Sclerosis-Associated Pulmonary Hypertension: A Systematic Review and Meta-Analysis. Arthritis Rheum 2013;65:2412-23. (IF : 6.918)
  2. 39. Launay D, Sitbon O, Hachulla E, Mouthon L, Gressin V, Rottat L, Clerson P, Cordier JF, Simonneau G, Humbert M. Survival in systemic sclerosis-associated pulmonary arterial hypertension in the modern management era. Ann Rheum Dis 2013;72:1940-6. (IF : 12.811)
  3. 40. Sivova N, Launay D, Wemeau-Stervinou L, De Groote P, Remy-Jardin M, Denis G, Lambert M, Lamblin N, Morell-Dubois S, Fertin M, Lefevre G, Sobanski V, Le Rouzic O, Hatron PY, Wallaert B, Hachulla E, Perez T. Relevance of Partitioning DLCO to Detect Pulmonary Hypertension in Systemic Sclerosis. PLoS One 2013;8. (IF : 2.806)
  4. 41. Hervier B, Meyer A, Dieval C, Uzunhan Y, Devilliers H, Launay D, Canuet M, Tetu L, Agard C, Sibilia J, Hamidou M, Amoura Z, Nunes H, Benveniste O, Grenier P, Montani D, Hachulla E*. Pulmonary hypertension in antisynthetase syndrome: prevalence, aetiology and survival. Eur Resp J 2013;42:1271-82. (IF : 10.569)
  5. 42. Bouillet L, Launay D, Fain O, Boccon-Gibod I, Laurent J, Martin L, Montauban V, Finck K, Bouee S, Gompel A, Kanny G. Hereditary angioedema with C1 inhibitor deficiency: clinical presentation and quality of life of 193 French patients. Ann Allergy Asthma Immunol 2013;111:290-4 (IF : 3.728)
  6. 43. Quéméneur T, Mouthon L, Cacoub P, Meyer O, Michon-Pasturel U, Vanhille P, Hatron PY, Guillevin L, Hachulla E*. Systemic vasculitis during the course of systemic sclerosis: report of 12 cases and review of the literature. Medicine (Baltimore). 2013 Jan;92(1):1-9. (IF : 1.804)

Review articles

2018

  1. 1. Pitoiset F, Barbié M, Monneret G, Braudeau C, Pochard P, Pellegrin I, Trauet J, Labalette M, Klatzmann D, Rosenzwajg M. A standardized flow cytometry procedure for the monitoring of regulatory T cells in clinical trials. Cytometry B Clin Cytom. 2018 Jan 6. (IF : 2.474)

2017

  1. 2. Sanges S, Guerrier T, Launay D, Lefèvre G, Labalette M, Forestier A, Sobanski V, Corli J, Hauspie C, Jendoubi M, Yakoub-Agha I, Hatron PY, Hachulla E, Dubucquoi S*. Role of B cells in the pathogenesis of systemic sclerosis. Rev Med Interne 2017;38:113-24. (IF : 1.126)
  2. 3. Launay D, Sobanski V, Hachulla E, Humbert M. Pulmonary hypertension in systemic sclerosis: different phenotypes. Eur Respir Rev 2017;26.
  3. 4. Launay D, Sobanski V*. [Pulmonary hypertension screening in systemic sclerosis: The best strategy remains to be defined]. Rev Med Interne 2017;38:499-501. (IF : 1.126)
  4. 5. Mortuaire G, Michel J, Papon JF, Malard O, Ebbo D, Crampette L, Jankowski R, Coste A, Serrano E. Specific immunotherapy in allergic rhinitis. Eur Ann Otorhinolaryngol Head Neck Dis. 2017 Jul 3. pii: S1879-7296(17)30102-3. doi: 10.1016/j.anorl.2017.06.005. (IF : 1.108)

2016

  1. 8. Sobanski V, Launay D, Hachulla E, Humbert M. Current Approaches to the Treatment of Systemic-Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH). Curr Rheumatol Rep 2016;18. (IF : 2.865)
  2. 9. Sobanski V, Launay D, Depret S, Ducloy-Bouthors AS, Hachulla E*. Special considerations in pregnant systemic sclerosis patients. Expert Rev Clin Immunol 2016;12:1161-73. (IF : 3.342)
  3. 10. Launay D*. Interstitial lung disease and systemic sclerosis. Rev Med Interne 2016;37:A16-A21. 64. (IF : 1.126)
  4. 11. Launay D*. A New Era in the Treatment of Scleroderma-associated Interstitial Lung Disease? J Rheumatol 2016;43:1619-21. (IF : 3.15)
  5. 12. Lefèvre G, Ackermann F, Kahn JE*. Hypereosinophilia with asthma and systemic (non-vasculitic) manifestations: Eosinophilic granulomatosis with polyangiitis or hypereosinophilic syndrome ?  Autoimmun Rev, 2016 Feb;16(2):208-209. (IF : 8.961)
  6. 13. Cluzeau T, Lambert J, Raus N, Dessaux K, Absi L, Delbos F, Devys A, De Matteis M, Dubois V, Filloux M, Fort M, Hau F, Jollet I, Labalette M, Masson D, Mercier B, Pedron B, Perrier P, Picard C, Quainon F, Ramounau-Pigot A, Renac V, Van Endert P, Charron D, Peffault de la Tour R, Taupin JL, Loiseau P. Risk factors and outcome of graft failure after HLA matched and mismatched unrelated donor hematopoietic stem cell transplantation: a study on behalf of SFGM-TC and SFHI. Bone Marrow Transplant. 2016 May;51(5):687-91. (IF : 3.874)

2015

  1. 14. Yelnik CM, Dubucquoi S, Houfflin-Debarge V, Lambert M. Antiphosphatidylethanolamine antibody as a marker of antiphospholipid syndrome? Presse Med. 2015. 44, 284–291. (IF : 1.071)

2013

  1. 15. Goeb V, Ardizzone M, Arnaud L, Avouac J, Baillet A, Belot A, Bouvard B, Coquerelle P, Dadoun S, Diguet A, Launay D, Lebouc D, Loulergue P, Mahy S, Mestat P, Mouterde G, Terrier B, Varoquier C, Verdet M, Puechal X, Sibilia J. Recommendations for using TNF alpha antagonists and French Clinical Practice Guidelines endorsed by the French National Authority for Health. Joint Bone Spine 2013;80:574-81. (IF : 3.329)